Jeff Franklin, creator of the television sitcom “Full House,” is putting his Beverly Hills estate, chock-full of outlandish amenities like a shark tank and waterslide, on the market for $85 million.

The roughly 21,000-square-foot, Andalusian-style estate, recognizable for its distinctive blue dome, sits on about 3.6 acres near Benedict Canyon and has nine bedrooms and 18 bathrooms, according to listing agents Josh and Matt Altman of Douglas Elliman.

The house was designed by architect Richard Landry, who is known for building megamansions for celebrities and business tycoons. Its amenities include a movie theater, spa, gym, hair salon, billiards room and bar. Outside, the property has a pool with three waterfalls, two hot tubs, a 35-foot waterslide, a swim-up bar, a private grotto, a koi pond and a lazy river.

“The problem with owning this house is just getting people to go home—they just don’t want to leave,” Mr. Franklin quipped. “It is great for little small dinner parties and you know, 500 people.”

Mr. Franklin bought the property roughly two decades ago. At the time it contained a partially completed mansion constructed by a developer, he said. He paid slightly more than $6 million for the property and then many millions more to finish the house, he said. He finally moved into the house in 2007.

The property is located on Cielo Drive, on land that once contained the house where the actress Sharon Tate and others were murdered by the Manson Family in 1969. The house where the murders occurred was demolished by a previous owner in the 1990s.

Mr. Franklin called the connection to the Manson murders “irrelevant” and “ancient history.” “It’s had absolutely no impact on my life whatsoever,” he said.

Mr. Franklin said his home’s unusual design was inspired by cultures from around the world.

“I wanted to incorporate all the influences that I love from various cultures around the world,” he said. In addition to Asian and European influences, “there’s a lot of California Casual, and then we add SeaWorld,” he said, noting that the property has six aquariums, including a shark tank, as well as a koi pond.

Mr. Franklin said the aquariums were partially inspired by his love of scuba diving. “This actually saves me a lot of traveling around the world,” he joked.

His favorite room is the bedroom, which he said has “drop dead views” over Los Angeles.

“I’ve got this giant TV that comes out of the ceiling and then disappears when I don’t want to watch it,” he said. “It’s got quite an amazing Balinese-style ceiling, and an indoor Jacuzzi in the bathroom that’s like a swimming pool.”

Mr. Franklin, who is 66 but said he could easily pass for 47, said he is selling the property because he recently relocated to Miami, where records show he has spent more than $48 million assembling land on the exclusive Venetian Islands. Noting that he was attracted to Miami’s tropical vibe and the boating lifestyle, he said he is in the final stages of designing a new home there with Mr. Landry, the same architect who designed the Beverly Hills home. He joked that he had paid so much for the land that people were putting up statues of him all around South Florida as thanks for how much he had driven up property values there.

“I swore I’d never do this again,” he said. “But I looked around and tried to find something that I liked there and I couldn’t find anything. So I just decided to bite the bullet and build something myself.”

Mr. Franklin is a screenwriter, director and producer. He served as a producer for the “Laverne & Shirley” show in the late 1970s and early 1980s. “Full House” ran on ABC from 1987 to 1995 and starred the late comedian Bob Saget; Mr. Franklin said he was deeply saddened by the recent death of Mr. Saget, with whom he was close.

Josh Altman said he believes the property is priced to sell. “The entertainment aspect of this house is untouchable by any other house in L.A., except for one other place that I have partied at: the Playboy Mansion,” he said. “The pool makes the ones at most of the resorts you’ve ever been at look small.”

Asked if he planned to include the sharks in the sale, Mr. Franklin wondered aloud if it was feasible to pump saltwater into a U-Haul and drive them to Miami.